Buy Zerodol SP Tablet: Uses, Side Effects, Price | Aum Pharmacy
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Zerodol SP Tablet


Zerodol-SP Tablets are a combination medication used to relieve pain and inflammation associated with arthritis, spondylitis, and postoperative pain. They contain aceclofenac, serratiopeptidase, and paracetamol, offering anti-inflammatory, analgesic, and antipyretic effects.

Prescription Required 


Ipca Laboratories Ltd


Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg) 


Store below 30°C or Store in a cool and dry place away from sunlight

SKU: PRO64 Category: Product ID: 10242


About Zerodol SP TABLET

Zerodol-SP Tablet is a combination medication designed to alleviate pain and swelling associated with various conditions such as muscle pain, joint pain, and postoperative discomfort. It effectively manages pain and inflammation in rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

To ensure optimal results, following your doctor’s recommended dosage and duration for taking Zerodol-SP Tablets are crucial. Taking Zerodol-SP with food or milk can help prevent stomach upset. Consistent, timely intake enhances its efficacy, so continue until your doctor advises otherwise.

Possible side effects include nausea, vomiting, stomach pain, dizziness, drowsiness, and diarrhea. Long-term usage may necessitate monitoring of kidney and liver function. It’s advised not to use Zerodol-SP Tablet during pregnancy or breastfeeding. This tablet, a blend of aceclofenac, Paracetamol, and serratiopeptidase, falls under the category of non-steroidal anti-inflammatory drugs (NSAIDs). It effectively reduces pain and inflammation from bone or soft tissue injuries, postoperative recovery, and reduced swelling.

Pain can be acute or chronic, from tissue damage or nerve-related issues like osteoarthritis or dental problems. Zerodol-SP Tablet can be taken with or without food and swallowed whole with water. Adverse effects like nausea or stomach discomfort are transient and may not necessitate medical intervention. However, if they persist, consulting your doctor is recommended.

Discontinuing Zerodol-SP Tablet without medical advice is not advised. Avoid if allergic to aspirin, ibuprofen, or similar medications, and do not exceed recommended dosage or duration. Zerodol-SP Tablet is contraindicated in children and individuals with specific medical conditions.

ZERODOL SP TABLET combines Aceclofenac, Paracetamol, and Serratiopeptidase to address inflammation, pain, and postoperative issues. It’s unsuitable for those allergic to its components or with certain medical conditions. Pregnant, breastfeeding women and minors should avoid it. Common side effects include abdominal discomfort and gastrointestinal issues. Promptly inform your doctor if these symptoms worsen.


Zerodol-SP Tablet is versatile in its applications, primarily addressing pain, inflammation, and swelling across various conditions. It serves as a remedy for:

  • Pain management post-injury
  • Alleviation of low back pain
  • Treatment for cervical pain
  • Relief from spondylitis
  • Management of osteoarthritis and rheumatoid arthritis

This combination medication, Zerodol SP tablet, effectively tackles pain, inflammation, and swelling associated with muscle pain, joint pain, postoperative discomfort, rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. Its uses include:

  • Providing relief from inflammation and pain resulting from bone and soft tissue injuries
  • Lowering fever and easing symptoms of cold
  • Resolving postoperative inflammation, edema, and pain
  • Mitigating ailments like headaches, moderate migraines, and musculoskeletal pain


Zerodol-SP Tablet offers a range of benefits, primarily focused on pain relief:

  • Short-term alleviation of pain, inflammation, and swelling in conditions impacting joints and muscles.
  • Functions by inhibiting chemical messengers in the brain responsible for signaling pain, thus providing relief.
  • Efficient in treating osteoarthritis and rheumatoid arthritis pain. 
  • Contains Serratiopeptidase, an enzyme that aids in healing and accelerates recovery.
  • Optimal benefits are achieved when taken as prescribed, avoiding excessive dosage or prolonged use to prevent potential risks.
  • It is recommended that the lowest effective dose be taken for the shortest duration possible, facilitating improved daily functioning and a higher quality of life.
  • Zerodol-SP Tablet 10’s formulation comprises aceclofenac, Paracetamol, and serratiopeptidase, each contributing to its pain-relieving and anti-inflammatory properties.
  • Aceclofenac blocks the action of cyclo-oxygenase (COX) enzyme, reducing pain and swelling in injured or damaged tissues.
  • Paracetamol acts as a mild analgesic and antipyretic, enhancing the pain relief effect of aceclofenac.
  • Serratiopeptidase facilitates smoother fluid drainage at the injury site, aiding in faster healing.
  • Collectively, these components alleviate pain and inflammation and support expedited healing processes.



  • Abdominal pain, nausea, vomiting, diarrhea, flatulence, constipation, indigestion
  • Dizziness, drowsiness
  • Stomach upset
  • Lack of appetite


  • Stomach inflammation
  • Skin inflammation, itching, red welts, rash
  • Kidney deterioration (nephrotoxicity), including interstitial nephritis, nephritic syndrome, and renal failure
  • Abnormal liver function, liver inflammation, signs of jaundice like yellowing of eyes and skin
  • Neurological effects such as visual disturbances, optic neuritis, headaches, abnormal sensations, reports of aseptic meningitis (especially in patients with autoimmune disorders)
  • Blood-related effects like low platelet or white blood cell counts, agranulocytosis, aplastic anemia, and hemolytic anemia


  • Signs of autoimmune skin disorders like exfoliative dermatitis or erythema multiforme
  • Anemia, signs of vasculitis such as fever, weakness, weight loss
  • Signs of anaphylactic reaction such as lightheadedness, wheezing, fast heartbeat
  • Face swelling, visual disturbance, shortness of breath
  • Skin rash with disease/fever

If you experience severe skin reactions (exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis), discontinue the Zerodol SP Tablet and consult your doctor immediately.



  • Consume high-fiber foods like vegetables, cereals, and fresh fruits.
  • Stay hydrated by drinking plenty of water.
  • Engage in regular exercises, like daily walks or runs.
  • Consult your doctor if symptoms persist despite lifestyle changes.


  • Maintain hydration by drinking ample water.
  • Avoid self-medication and seek medical advice if symptoms worsen.

Dizziness or Drowsiness:

  • Ensure adequate rest and sleep.
  • Avoid driving or operating machinery while experiencing dizziness.
  • Limit alcohol intake as it may exacerbate symptoms.
  • Inform your doctor if symptoms worsen.


  • Eat more often and in smaller portions, and take your time. 
  • Cut down on coffee, cola, tea, or alcohol consumption.
  • Consider weight loss if overweight.
  • Avoid smoking and rich, fatty, or spicy foods.
  • Consult your doctor if symptoms persist.

Nausea and Vomiting:

  • Take Zerodol SP Tablet with or after a meal or snack.
  • Stick to simple, bland meals and avoid rich or spicy foods.
  • Seek medical advice if symptoms worsen.


Take the Zerodol-SP Tablet precisely as your doctor has advised. Take the tablet whole and swallow it with a glass of water; do not break, chew, or crush it. This medication should be taken with food to help prevent stomach upset. The correct dose and duration will be determined by your doctor based on your age, body weight, and specific condition. The combination medication Zerodol-SP Tablet treats pain, inflammation, and swelling brought on by several illnesses, such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle and joint pain, and postoperative pain. 


Zerodol-SP Tablet combines three active ingredients: Aceclofenac, Paracetamol, and Serratiopeptidase. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol, an antipyretic (fever reducer), work by blocking the release of certain chemical messengers in the brain that cause pain and fever. An enzyme called serratiopeptidase aids in the healing process by dissolving aberrant proteins at the site of inflammation. Together, these components reduce inflammation, alleviate pain, and support the healing process at the injury site.


Interactions with Other Medicines

  • Paracetamol or Aceclofenac: Avoid taking other medicines containing these ingredients to prevent liver damage.
  • High Blood Pressure Medications: Zerodol-SP can reduce the effectiveness of these drugs.
  • Diuretics (Water Pills): Concurrent use can lead to kidney damage.
  • Heart Failure Medications, Lithium, Methotrexate: Use caution due to potential adverse effects.
  • Immune-Modifying Drugs (Ciclosporin & Tacrolimus): Can cause kidney damage when taken with Zerodol-SP.
  • Steroids and Other Pain Relievers (Aspirin): Increases the risk of stomach ulcers or bleeding.
  • Blood Thinners (Warfarin, Coumarin): Heightens the risk of bleeding.
  • Antibiotics (Levofloxacin, Ciprofloxacin): Raise the risk of seizures.
  • Diabetes Medications: Watch for symptoms of low blood sugar, such as sweating, anxiety, fast heartbeat, and hunger pangs.
  • Seizure and Depression Medications (Phenobarbital, Carbamazepine, Phenytoin, Clonazepam) Should be taken cautiously due to possible interactions.


Q: What is Zerodol-SP Tablet?

– Zerodol-SP Tablet combines three medicines: Aceclofenac, Paracetamol, and Serratiopeptidase. It relieves pain and inflammation by lowering the levels of chemical substances in the body that cause these symptoms.

Q: Is it safe to take Zerodol-SP Tablet?

– Zerodol-SP Tablet is generally safe for most patients. Still, it may cause side effects like nausea, vomiting, stomach pain, heartburn, and diarrhea. If you experience any persistent issues, inform your doctor promptly.

Q: Can I stop using Zerodol-SP Tablets once my pain subsides? 

– You can usually stop taking Zerodol-SP Tablet once your pain is relieved, but if you have been instructed to continue, follow your doctor’s advice.

Q: Can Zerodol-SP Tablet cause nausea and vomiting?

– Yes, nausea and vomiting are possible side effects. To minimize these, take the tablet with food, milk, or antacids, and avoid fatty or fried foods. If vomiting persists, stay hydrated and consult your doctor.

Q: Can Zerodol-SP Tablet cause dizziness?

– Yes, dizziness can occur in some patients. If you feel dizzy, rest until you feel better before resuming activities.

Q: Are there any specific contraindications for taking Zerodol-SP Tablet?

– Zerodol-SP Tablet should not be used by patients allergic to any of its components or other NSAIDs or by those with a history of stomach ulcers, heart failure, high blood pressure, or liver or kidney disease.

Q: Can I take a Zerodol-SP Tablet with vitamin B-complex?

– Zerodol-SP can be taken with vitamin B-complex supplements, which may help address any vitamin deficiencies contributing to your symptoms.

Q: Can the use of Zerodol-SP Tablet cause kidney damage?

– Long-term use of Zerodol-SP Tablet can cause kidney damage, especially in patients with underlying kidney conditions. Consult your doctor for regular monitoring if you need long-term treatment.

Q: Is taking a higher dose of Zerodol-SP Tablet safe than recommended?

– No, do not exceed the recommended dose. If your pain persists or worsens, consult your doctor for re-evaluation.

Q: What are the instructions for storage and disposal of Zerodol-SP tablets?

– Store the medicine in its original packaging, tightly closed, and according to the instructions on the label. Dispose of unused medicine responsibly, keeping it out of reach of pets, children, and others.

Q: Is it safe to take Zerodol-SP Tablet 10’s?

– Zerodol-SP Tablet 10 is generally safe but may cause side effects such as diarrhea, vomiting, or nausea. Consult your doctor if any side effects occur.

Q: In what conditions is Zerodol-SP Tablet 10’s contraindicated?

– Zerodol-SP Tablet 10’s should be avoided in individuals allergic to painkillers or NSAIDs and those with heart failure, kidney or liver disease, and stomach ulcers.

Q: What is rheumatoid arthritis?

– Rheumatoid arthritis is a chronic inflammatory disorder that affects joints, including the hands and feet. In severe cases, it can also affect internal organs.

Q: What is ankylosing spondylitis?

– Ankylosing spondylitis is a rare type of arthritis that causes pain and stiffness in the spine, starting in the lower back and potentially spreading to the neck.

Q: Can I take Zerodol-SP Tablet for stomach pain?

– No, Zerodol-SP Tablet is not indicated for stomach pain. Consult your doctor for appropriate treatment.

Q: Can Zerodol-SP Tablet be taken with alcohol?

– Avoid or limit alcohol intake while taking Zerodol-SP Tablet, as it can increase the risk of liver damage.

Q: Can I take Zerodol-SP Tablet with other painkillers?

– Avoid taking other painkillers with Zerodol-SP Tablet without consulting your doctor, as it can lead to adverse effects like gastrointestinal bleeding and liver damage.

Q: Is Zerodol-SP an antibiotic medicine?

– Zerodol-SP is a painkiller and anti-inflammatory medicine, not an antibiotic.

Q: What are the side effects of taking Zerodol-SP tablets?

– Common side effects include nausea, diarrhea, indigestion, stomach pain, and dizziness.

Q: Can I take Zerodol-SP for period pain?

– Zerodol-SP is not typically used for period pain. Consult your doctor for appropriate treatment options.

Q: Can I take Zerodol-SP for a toothache?

– Consult your dentist before taking Zerodol-SP for a toothache.

Q: How does Zerodol-SP work?

– Zerodol-SP combines Paracetamol, aceclofenac, and serratiopeptidase to reduce pain and inflammation and promote healing.

Q: Is Zerodol-SP a painkiller?

– Yes, Zerodol-SP is an analgesic and anti-inflammatory medicine.

Q: Can Zerodol-SP be used by people with diabetes?

– Diabetics should consult their doctor before taking Zerodol-SP, as it may interact with antidiabetic medications.

Q: Can Zerodol-SP be taken without food?

– It is recommended to take Zerodol-SP with food to avoid gastrointestinal irritation.

Q: Can I take a double dose of Zerodol-SP for faster results?

– Always follow your doctor’s prescribed dosage to avoid side effects.

Q: Can Zerodol-SP be used for fever?

– Zerodol-SP can reduce fever but should only be used under a doctor’s prescription.

Q: How can I order Zerodol-SP Tablets from Aum Pharmacy?

– You can order Zerodol-SP Tablets at best discounted price online from Aum Pharmacy with a prescription. Search for the product, add it to your cart, and proceed to checkout. Aum Pharmacy is a leading online pharmacy in India.


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