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Dolo 650MG Tablet


Dolo 650 Tablet is a widely used medication known for its effectiveness in reducing fever and relieving mild to moderate pain. Each tablet typically contains 650 milligrams of paracetamol (also known as acetaminophen), the active ingredient responsible for its therapeutic effects.


Micro Labs Ltd


Paracetamol (650mg)




Store below 25°C

SKU: PRO71 Category: Product ID: 10268



Dolo 650 Tablet, a widely prescribed paracetamol-based medication, effectively alleviates pain and fever by inhibiting the release of specific chemical messengers responsible for these symptoms. It is commonly used to treat conditions such as headaches, migraines, toothaches, sore throats, menstrual pains, arthritis, muscle aches, and fevers associated with colds or flu.

During the COVID-19 pandemic, the Dolo 650 Tablet emerged as one of the most recommended medications. It should be taken regularly per the doctor’s advice, preferably with food to avoid stomach upset. However, the dosage should be at most four tablets in 24 hours, with at least a 4-hour gap between doses. It’s essential not to prolong the use beyond the recommended duration.

While generally well-tolerated, some individuals may experience temporary side effects such as stomach pain, nausea, or vomiting. It is best to consult a doctor if these adverse effects worsen or continue. Before taking the Dolo 650 Tablet, it’s crucial to inform the doctor about any existing liver or kidney problems, allergies, or concurrent medications to ensure its suitability and dosage adjustments if necessary.

Dolo 650 Tablet contains Paracetamol, which blocks the body’s formation of pain and fever-causing chemicals. The dosage and duration of Dolo 650 may vary depending on the condition and symptoms. It is essential not to exceed the recommended dosage and to discontinue use once the fever and pain subside. Avoid giving Dolo 650 to children under 12 without consulting a doctor.

Apart from Dolo 650 Tablet, other medications such as Crocin 650mg Advance, Lanol Er 650mg, P 650mg, and Dolopar 650mg contain Paracetamol as their active ingredient.


  • Dolo 650 Tablet is versatile, offering relief from pain and reducing fever.
  • It effectively addresses mild to moderate headaches, migraines, toothaches, and menstrual cramps.
  • The medication helps alleviate various body aches, including joint and back pain.
  • It aids in lowering fevers associated with common colds or flu.
  • Dolo 650 Tablet is beneficial for managing pain and fever in sore throat conditions.
  • It also assists in easing arthritis-related pain and discomfort.
  • Additionally, the medication helps reduce reactions post-vaccination, enhancing its utility in diverse situations.


  • Pain Relief: The Dolo 650 Tablet is a trusted painkiller, effectively alleviating aches and pains.
  • Fever Reduction: It works by blocking the release of specific chemical messengers that cause fever, helping to reduce high body temperatures.
  • Widely Used: Dolo 650 Tablet is a commonly prescribed medication for managing pain and fever.
  • Minimal Side Effects: It rarely causes significant adverse effects when prescribed, ensuring safer usage.
  • Prescription Guidance: Adhering to the prescribed dosage and duration is crucial to optimizing its benefits and minimizing risks.
  • Combination Therapy: It can be prescribed alone or in combination with other medications to effectively address different medical conditions.
  • Active Ingredient: Contains Paracetamol, which acts as both an analgesic (pain reliever) and antipyretic (fever reducer).
  • Mechanism of Action: It inhibits the production of prostaglandins in the brain, regulates body temperature, reduces pain sensations, and enhances overall comfort.


  • Common Side Effects: Both Dolo 650 tablets and Dolo 650 MG tablets may lead to common side effects, including nausea, stomach pain, and vomiting. These effects are typically mild and often subside as the body adjusts to the medication.
  • Rare Occurrences: While side effects are uncommon when adhering to recommended doses, there’s a slight possibility of experiencing skin rash, itching, blisters, or allergic reactions with Dolo 650 MG.
  • Consultation Advised: If these side effects persist or cause concern, it’s essential to consult a healthcare professional. They can provide guidance and address any potential issues related to the medication’s usage.


To address potential side effects, it’s crucial to note that most are transient and pose minimal harm. However, seeking medical advice is advisable if any severe symptoms arise or existing ones worsen.

Below are some basic strategies for managing common side effects:

  1. Nausea: Consider consuming a Dolo-650 Tablet alongside a meal to alleviate nausea.
  2. Stomach Pain and Vomiting: If stomach discomfort persists, taking the medication after eating may help alleviate these symptoms.


To ensure proper usage of the Dolo 650 Tablet, adhere to your doctor’s instructions regarding dosage and duration. Swallow the tablet whole with a glass of water without chewing or crushing it. Taking it with food is preferable to minimize the risk of stomach discomfort.

Dosage instructions may vary, so follow your physician’s recommendations precisely. Refrain from exceeding the prescribed dosage. Maintain a gap of at least four hours between each dose of Dolo 650 Tablet to avoid potential complications.


Dolo 650 Tablet and Dolo-650 Tablet 15 work similarly in the body. They are both analgesics (pain relievers) and antipyretics (fever reducers). Their mechanism involves blocking the release of specific chemical messengers responsible for pain and fever.

The active ingredient in both tablets, Paracetamol, inhibits the production of prostaglandins, chemicals in the body associated with pain and inflammation. By targeting prostaglandins, these medications alleviate discomfort and reduce fever.

Moreover, Paracetamol acts in the brain, particularly in the hypothalamus, where it helps regulate body temperature. By modulating prostaglandin activity in this region, it aids in controlling fever.

Additionally, Paracetamol alters pain perception by affecting how nerve signals transmit pain messages to the brain. This adjustment reduces the sensation of pain, providing further relief.


  1. Alcohol: It’s unsafe to consume alcohol while taking Dolo 650 Tablets due to the risk of liver damage.
  2. Pregnancy: Dolo 650 Tablet may be unsafe during pregnancy, as animal studies suggest potential harm to the baby. Consult your doctor before use.
  3. Breastfeeding: Using Dolo 650 Tablet during breastfeeding is generally safe, as studies show minimal transfer to breast milk.
  4. Driving: The Dolo 650 Tablet typically doesn’t affect driving ability.
  5. Kidney: Caution is advised in patients with kidney disease. Dosage adjustments may be necessary.
  6. Liver: Use caution when dealing with liver disease patients. Avoid in cases of severe liver disease.
  7. Allergy: Avoid Dolo 650 Tablets if allergic to Paracetamol.
  8. Paediatrics: Consult a doctor before giving Dolo 650 Tablets to children under 10.
  9. Geriatrics: Use cautiously in elderly patients with liver issues.

Additionally, inform your doctor if you have sepsis (blood infection) before taking the Dolo 650 Tablet.


  1. Enhance Absorption: Take Dolo 650 Tablets with a small snack or a glass of milk to optimize absorption and minimize stomach discomfort.
  2. Adhere to Prescription: Strictly follow the prescribed dose and duration recommended by your healthcare provider to mitigate the risk of potential complications such as gastrointestinal bleeding and renal issues associated with prolonged usage.
  3. Time Intervals: Ensure a sufficient time gap between taking Dolo 650 tablets and indigestion remedies (antacids) to prevent any interference with its effectiveness.
  4. Alcohol Avoidance: While using the Dolo 650 Tablet, it’s advisable to abstain from alcohol consumption to reduce the likelihood of gastrointestinal complications and liver damage.
  5. Liver Health Awareness: Be proactive in informing your doctor about any existing liver conditions, as they may need to adjust your dosage accordingly. Monitoring liver function, kidney function, and blood components is essential for prolonged treatment.
  6. Pain Management Strategy: Employ Dolo 650 tablets to alleviate a spectrum of discomforts, including dental pain, headaches, and menstrual cramps, by effectively intercepting pain and fever-inducing neurotransmitters.
  7. Dosage Distribution: For consistent relief, maintain a disciplined approach by limiting Dolo 650 tablet intake to four doses within 24 hours, spaced evenly apart every four to six hours.
  8. Vigilance for Side Effects: While adverse reactions to Paracetamol are infrequent, remain vigilant for any signs of skin irritation, rash, or allergic responses that warrant prompt medical attention.
  9. Pediatric Caution: Keep Dolo 650 tablets out of reach for children under 12 years old, and ensure a sufficient interval of 4-6 hours between successive doses to prevent overdosing.
  10. Pregnancy Protocol: Exercise caution during pregnancy, using Dolo 650 tablets under medical supervision in small, intermittent doses for short durations to mitigate potential risks to fetal health. Always consult your doctor before use.


  • Store Dolo 650 tablets in a cool, dry place away from direct sunlight and moisture. To maintain the medication’s efficacy, the recommended storage temperature should not exceed 25°C or 30°C.
  • Safeguard the tablets by keeping them out of reach of children and pets, ensuring they are stored securely to prevent accidental ingestion.
  • Prioritize storage in a dark area to minimize exposure to light, which can degrade the medication over time.
  • Check the expiry date on the packaging regularly to ensure the medication’s potency and effectiveness before consumption or disposal.
  • Dispose of any expired or unused medication responsibly, following local regulations and guidelines to minimize environmental impact and ensure safety.


Before consuming Dolo 650 tablets, it’s crucial to be aware of potential interactions, especially if you are taking other medications. Here’s what you need to know:

  1. Drug-Drug Interactions:
    • Inform your healthcare provider about all the medications you are currently taking, including other Paracetamol pain relievers, medications for nausea and vomiting like metoclopramide or domperidone, and cholesterol-lowering drugs like cholestyramine.
    • Be cautious taking blood thinners such as warfarin or antibiotics like rifampicin, flucloxacillin, or chloramphenicol, as they may interact with Dolo 650 tablets.
  2. Overdosage Concerns:
    • In the event of an accidental overdose, seek immediate medical attention, even if you feel well. Overconsumption of Dolo 650 tablets can lead to severe liver damage, emphasizing the importance of prompt medical intervention.

Drug Warnings:

  1. Allergic Reactions: Do not use Dolo-650 Tablet 15s if you have a known allergy to it. It’s also not recommended for children under 6 years old. Consult a physician if you are pregnant, breastfeeding, or have an impaired nutritional state, dehydration, or anorexia.
  2. Alcohol: Avoid consuming alcohol while taking Dolo-650 Tablet 15s to reduce the risk of liver damage.
  3. Dosing: Stick to the recommended doses to avoid the potential for severe liver damage.

Drug Interactions:

  1. Drug-Drug Interactions: Dolo-650 Tablet 15’s may interact with various medications, including blood thinners, cholesterol-lowering drugs, analgesics, antibiotics, anti-gout medicines, antitubercular drugs, anticonvulsants, and anti-nausea agents.
  2. Drug-Food Interactions: Be cautious of interactions with St. John’s wort and foods rich in carbohydrates and pectin, as they may affect the efficacy of Dolo-650 Tablet 15.
  3. Drug-Disease Interactions: Inform your physician if you have kidney or liver disease, hepatitis, Gilbert’s syndrome, hemolytic anaemia, G-6-PD deficiency, or blood poisoning before taking Dolo-650 Tablet 15’s.

Diet & Lifestyle Advice:

  1. Sleep: Ensure adequate rest to reduce inflammation and swelling.
  2. Heat/Cold Therapy: Regularly apply hot or cold compresses to affected joints.
  3. Alternative Therapies: Consider acupuncture, massage, and physical therapy.
  4. Antioxidant-rich Foods: To help reduce inflammation, incorporate berries, spinach, dark chocolate, and foods containing flavonoids into your diet.
  5. Maintain Healthy Weight: Engage in regular, low-strain exercises and follow a balanced diet.
  6. Avoid Smoking and Alcohol: Minimize smoking and alcohol consumption for overall health benefits.


Q: What’s the DOLO 650 Tablet used for?

– DOLO 650 Tablet is your go-to for tackling fever and all sorts of aches and pains, whether from a headache, sore throat, joint pain, or even the common cold or flu.

Q: What’s the deal with DOLO 650 Tablet?

– DOLO 650 Tablet contains Paracetamol, a natural multitasker that’s both a painkiller and a fever reducer. It blocks those pesky pain-causing chemicals in your body and helps keep your fever in check.

Q: Can I pop two DOLO 650 Tablets in one day?

– Your doctor usually has the final say on this, but studies suggest spacing out paracetamol doses every 4-6 hours can help fight fever and pain.

Q: Can the DOLO 650 Tablet help with a cold?

– Absolutely! It’s not just for fever—DOLO 650 Tablet can help ease the throat and body pains that often come with colds. Plus, it’s got your back for headaches, muscle aches, and toothaches.

Q: Can I take DOLO 650 Tablet whenever I feel like it?

– It’s best to follow your doctor’s advice. Usually, the best approach is to keep it to no more than 4 doses a day, with a 4-6 hour gap in between.

Q: Is the DOLO 650 Tablet powerful?

– It’s a solid choice for reducing mild to moderate pain and fever. Just remember, following the recommended dose is critical to keeping things safe.

Q: How soon does the DOLO 650 Tablet start working?

– Give it about half an hour, and you should start feeling the relief kick in. Just be sure to follow your doctor’s instructions and watch for any side effects.

Q: Can I mix DOLO 650 Tablet with ibuprofen?

– It’s generally only recommended if your healthcare provider gives the green light. Mixing them up could lead to unwanted side effects, especially for your liver and stomach.

Q: When should I give the DOLO 650 Tablet a rain check?

– If you start noticing allergic reactions, skin troubles, or signs of liver issues like nausea or yellowing skin, it’s best to pause and chat with your doctor.

Q: Is DOLO 650 Tablet an antibiotic?

– Nope, it’s more of a pain-relief pro than an infection fighter. It’s all about bringing down the fever and easing the pain.

Q: What if I go overboard with DOLO 650 Tablet?

– Taking more than the recommended dose can spell trouble, potentially affecting your liver and tummy. If you start feeling off, like with vomiting or stomach pains, it is best to dial up your doctor.

Q: Can the DOLO 650 Tablet be my headache hero?

– Absolutely! It’s got the power to soothe your head woes. But if those headaches keep returning, it might be time to team up with your doctor for a game plan.

Q: How about DOLO 650 Tablets during pregnancy?

– While it’s usually okay, avoiding it in the last trimester days is best. To keep things chill, stick to the smallest dose for the shortest time.

Q: What if I take DOLO 650 without a fever?

– No worries! It’s safe and sound for tackling other pesky pains, such as headaches or muscle spasms.

Q: Can I snag some DOLO 650 tablets from an online pharmacy?

– Yup, you sure can! Just double-check your prescription deets and follow all the buying rules. And hey, it’s always good to loop in your doc before making any moves.

Q: How can I Buy or order a DOLO 650 Tablet from Aum Pharmacy?

– You can Buy or order DOLO 650 tablets online with a prescription at the best-discounted price from Aum Pharmacy. Search for the product, add it to your cart, and proceed to checkout. Aum Pharmacy is a leading online pharmacy in India.


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