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Metrogyl 400mg Tablet


Metrogyl 400 Tablet 15 contains metronidazole, an antibiotic and antiprotozoal medication. It’s commonly used to treat bacterial and protozoal infections in various parts of the body, including the gastrointestinal and genital tracts and the skin. It’s essential to use Metrogyl 400 only as a healthcare professional prescribes to ensure effective treatment and minimize the risk of side effects.

Prescription Required


J B Chemicals and Pharmaceuticals Ltd


Metronidazole (400mg)


Store below 30°C

SKU: PRO76 Category: Product ID: 10274



Metrogyl 400 Tablet 15 is an antimicrobial medicine that treats various bacterial and parasitic infections. These include diseases of the blood, brain, lungs, bones, pelvic area, stomach lining, intestines, gums, teeth, post-childbirth or post-operative wounds, infected leg ulcers, pressure sores, and stomach ulcers caused by Helicobacter pylori. It’s also effective against urinary or genital infections caused by the Trichomonas parasite and amoebiasis (a parasitic infection of the colon), and it helps prevent infections following surgery.

The active ingredient, Metronidazole, works by inhibiting the production of proteins necessary to survive harmful microorganisms, thus treating the infections.

Your doctor will determine the duration of treatment for the type of infection. Common side effects include nausea, vomiting, upset stomach, loss of appetite, dry mouth, and a metallic taste. These side effects typically do not require medical attention and should resolve over time. However, consult your doctor if they persist or worsen.

Metrogyl 400 Tablet 15’s is not recommended during pregnancy, especially in the first trimester and while breastfeeding. It may cause dizziness and drowsiness, so avoid driving or operating heavy machinery after taking it. Avoid alcohol during treatment and for 48 hours after completing the course, as it can cause unpleasant side effects. Inform your doctor about your health condition and any other medications you are taking to prevent potential side effects.


Metrogyl 400mg Tablet is used to treat a variety of bacterial and parasitic infections, including:

  • Amoebiasis and Giardiasis (parasitic infections causing severe diarrhea and stomach cramps)
  • Genital or urinary tract infections (such as trichomonas vaginitis)
  • Blood infections
  • Brain infections (such as meningitis)
  • Lung infections
  • Stomach infections (e.g., H. pylori infection)
  • Pelvic area infections
  • Gum and tooth infections
  • Infected leg ulcers or pressure sores

Additionally, it effectively manages post-surgical infections and infections that occur after childbirth.


In Treatment of Bacterial Infections

Metrogyl 400 Tablet is a versatile antibiotic used to treat various bacterial infections, including those in the blood, brain, lungs, bones, joints, urinary tract, stomach, and intestines. It also effectively treats gum ulcers, dental infections (abscesses), leg ulcers, and pressure sores. The tablet works by inhibiting the growth of the bacteria causing the infection.

This medicine typically provides quick relief. However, completing the prescribed course is essential to eliminate all bacteria and prevent resistance. Metrogyl 400 Tablet is generally safe during pregnancy and breastfeeding, but you should consult your doctor.

In Treatment of Parasitic Infections

Metrogyl 400 Tablet also treats various parasitic infections, such as amoebic dysentery, by stopping the growth of the parasites causing the infection. This medicine often makes you feel better quickly. Still, it’s crucial to continue taking it for the entire prescribed duration to ensure all parasites are eradicated and do not develop resistance. This medicine is generally safe for use during pregnancy and breastfeeding, but you should seek advice from your doctor.



  • Loss of appetite
  • Nausea, vomiting, diarrhea
  • Metallic taste in the mouth
  • Stomach cramps
  • Headache, dizziness
  • Swelling or inflammation of the tongue
  • Dry mouth
  • Skin flushing, rash, itching
  • Genital itching
  • Pharyngitis and sinusitis

Stop taking Metrogyl 400MG Tablet and consult your doctor immediately if you experience:

  • Severe stomach pain, loss of appetite, nausea, vomiting, fever, fatigue, jaundice (yellowing of skin and eyes), dark urine, light-colored stools, skin itchiness
  • Signs of severe allergic reactions (rash, itching, swelling of the face, lips, throat, or tongue causing difficulty in breathing or swallowing)
  • Severe skin reactions (widespread rash, blistering, peeling, or bleeding with fever, chills, enlarged lymph nodes, and malaise or pink/reddish lesions on palms or soles)
  • Signs of encephalopathy (fever, stiff neck, headache, hallucinations, confusion, difficulty using arms and legs, speech problems)
  • Signs of blood disease (unexpected infections, mouth ulcers, bruising, gum bleeding, severe tiredness)
  • Signs of liver problems (yellowing of skin and eyes)
  • Severe stomach pain reaching through to your back (signs of pancreatitis)



  • Drink plenty of fluids like water or fruit juice to stay hydrated. ORS can be beneficial. Avoid self-medicating without consulting your doctor. Seek medical advice if diarrhea worsens.


  • Rest and relax. Stay hydrated with water or electrolytes. Apply pain-relieving balm on your forehead. Avoid excessive alcohol as it may worsen the headache. Consult your doctor if the headache persists.

Nausea and Vomiting

  • Take Metrogyl 400MG Tablet with or after meals. Steer clear of greasy or spicy foods and stick to simple meals. Consult your doctor if symptoms worsen.

Skin Rash or Itching

  • Avoid hot showers to prevent further skin irritation. Do not scratch the affected area. Wear protective clothing when outdoors. Moisturize your skin regularly. Consult your doctor if the rash worsens.

How Metrogyl 400 Tablet Works

Metrogyl 400 Tablet contains the active ingredient metronidazole, which targets bacterial and parasitic infections. Here’s how it works:

  • DNA Damage: Metronidazole damages the DNA of bacteria and other microorganisms, preventing them from replicating and growing.
  • Broad-Spectrum Activity: It is effective against many bacteria and parasites.
  • Targeted Action: The drug penetrates infected tissues, delivering its antimicrobial effects directly where needed.
  • Toxic Compound Formation: Metronidazole forms toxic compounds within microbial cells, disrupting essential metabolic pathways.
  • Anti-Inflammatory Properties: It also helps reduce inflammation associated with certain infections.
  • Anaerobic Bacteria: Its effectiveness against anaerobic bacteria makes it particularly useful for treating infections in low-oxygen environments.
  • Absorption: Metronidazole is well-absorbed from the gastrointestinal tract and reaches therapeutic levels in various body tissues.

Storage Guidelines for Metrogyl 400 Tablet

  • Keep Metrogyl 400 Tablet stored at temperatures below 30°C.
  • Shield the medicine from both light and moisture.
  • Ensure it remains inaccessible to children.
  • Utilize the product before its expiration date.

In-depth Information

Drug Precautions

  • Do not use Metrogyl 400 Tablet 15s if you have allergies to any of its components. Pregnant women, especially in the first trimester, should avoid its use.
  • Inform your doctor about pregnancy or plans for pregnancy. Avoid breastfeeding during and for 12-24 hours after completing the course.
  • Refrain from driving or operating heavy machinery due to potential dizziness and drowsiness post-consumption.
  • Notify your doctor if you have conditions such as Clostridium difficile-associated diarrhea, bone marrow depression, CNS disorders, epilepsy, porphyria, peripheral neuropathy, or heart, kidney, or liver issues.


  • Metrogyl 400 Tablet 15 may interact with HIV medications, anticoagulants, certain vaccines, anti-cancer drugs, and ethanol-containing medications.
  • Avoid alcohol consumption during treatment and 48 hours after to prevent adverse effects like nausea, vomiting, stomach pain, palpitations, headache, and hot flashes.

Dietary and Lifestyle Recommendations

  • Consider taking probiotics after completing the course to restore healthy gut bacteria and reduce the risk of antibiotic-associated diarrhea.
  • Include fiber-rich foods like whole grains, yogurt, cheese, sauerkraut, and kimchi to promote the growth of beneficial gut bacteria.
  • Avoid alcohol consumption to prevent dehydration and sleep disturbances, aiding Metrogyl 400 Tablet 15’s effectiveness in fighting infections.
  • Maintain hydration and drink fluids appropriately if experiencing diarrhea to prevent dehydration.

Drug Interactions

Drug-Drug Interactions:

  • Metrogyl 400 Tablet may interact with antibiotics like ciprofloxacin and clarithromycin, anticoagulants such as warfarin or heparin, antifungal medications including fluconazole and ketoconazole, and psychiatric drugs like lithium or phenobarbital.

Drug-Food Interactions:

  • Avoid alcohol consumption while on Metrogyl 400 Tablet to prevent potential adverse reactions.

Drug-Disease Interactions:

  • Notify your doctor if you have nervous system disorders or kidney or liver problems.

Dosage Instructions

Daily Dose:

  • Take 400 tablets of Metrogyl with food daily at the same time. Adhere strictly to your doctor’s directions.


  • In case of accidental overdose, promptly seek medical attention. Symptoms may include nausea, vomiting, stomach pain, and headaches.

Missed Dose:

  • Take the missed dose as soon as you remember. However, if your next scheduled dose is nearing, skip the missed one. Only double up on doses by consulting your doctor.



Monitoring Required

  • Avoid METROGYL 400MG TABLET during pregnancy unless prescribed by a physician. Consult your doctor before use.



  • Avoid METROGYL 400MG TABLET while breastfeeding due to potential transfer through breast milk. Consult your doctor before use.


Use with Caution

  • METROGYL 400MG TABLET may cause dizziness or drowsiness. Avoid driving or operating heavy machinery if affected.


Consult Your Doctor

  • Avoid alcohol consumption while on METROGYL 400MG TABLET to prevent adverse effects. Consult your doctor for guidance.


Use with Caution

  • Use METROGYL 400MG TABLET cautiously in patients with kidney issues. Consult your doctor before use.


Use with Caution

  • Exercise caution in patients with liver problems when taking METROGYL 400MG TABLET. Consult your doctor before use.



  • Do not take METROGYL 400MG TABLET if allergic to Metronidazole.


Use with Caution

  • Exercise caution when using METROGYL 400MG TABLET in children and adolescents. Consult your doctor before use.


Use with Caution

  • Use METROGYL 400MG TABLET cautiously in elderly patients. Consult your doctor before use.


Before taking METROGYL 400MG TABLET, inform your doctor about nervous system diseases, Cockayne syndrome, or blood dyscrasias.

Quick Tips for Metrogyl 400 Tablet

  • Metrogyl 400 Tablet effectively treats bacterial and parasitic infections, but be aware of potential side effects, such as nausea, stomach upset, and a metallic taste in your mouth.
  • Stick to the prescribed dosage and duration to minimize the risk of side effects, particularly nerve damage.
  • Avoid alcohol consumption during treatment and for a few days after, as it may lead to unpleasant reactions like nausea, vomiting, flushing, and headache.
  • If you have liver disease, inform your doctor, as dosage adjustments may be necessary.
  • Always follow your doctor’s instructions regarding dosage and completion of the treatment course.
  • Keep Metrogyl 400 Tablets stored below 30°C, out of reach of children.


Q: How is the METROGYL 400MG TABLET used? 

– METROGYL 400MG TABLET is prescribed to manage various parasitic infections like amoebiasis, Giardiasis, and trichomonas vaginitis, as well as bacterial infections affecting different body parts, including the blood, brain, lungs, stomach (e.g., H. pylori infection), bones, pelvis, urinary and genital tracts, gums, teeth, and infected leg ulcers or pressure sores. It’s also practical for post-surgical and post-childbirth infections.

Q: How does METROGYL 400MG TABLET work in my body?

– METROGYL 400MG TABLET inhibits bacteria and parasites, disrupting their DNA and preventing further growth and multiplication. This action helps to control and reduce the severity of infections.

Q: What precautions need to be taken during management with METROGYL 400MG TABLET?

– Before taking METROGYL 400MG TABLET, inform your doctor about any liver or kidney issues, nervous system disorders, or if you’re pregnant or breastfeeding. Completing the entire course of treatment is crucial for effective infection control. Avoid alcohol consumption during and for a few days after taking METROGYL 400MG TABLET to prevent dizziness and drowsiness.

Q: Can METROGYL 400MG TABLET be used in children?

– METROGYL 400MG TABLET should be used cautiously in children and adolescents. Consult your doctor for the appropriate dosage and duration of therapy based on age, weight, and infection severity.

Q: Can METROGYL 400MG TABLET manage viral infections?

– No, METROGYL 400MG TABLET is not effective against viral infections. It’s specifically designed to treat bacterial and parasitic infections.

Q: What kind of infections can METROGYL 400MG TABLET manage?

– METROGYL 400MG TABLET is effective against bacterial and parasitic infections, including those affecting the blood, brain, lungs, stomach, bones, pelvis, urinary and genital tracts, gums, teeth, and infected leg ulcers or pressure sores.

Q: Is it possible for METROGYL 400MG TABLET usage to induce diarrhea? 

– Yes, METROGYL 400MG TABLET may cause diarrhea. If you experience this side effect, stay hydrated and consult your doctor if it persists.

Q: Should I stop taking METROGYL 400MG TABLET once my symptoms subside?

– No, complete the entire course of METROGYL 400MG TABLET as prescribed by your doctor to ensure adequate infection control and prevent symptom recurrence.

Q: What are the common side effects of METROGYL 400MG TABLET?

– Common side effects include lack of appetite, nausea, metallic taste in the mouth, and stomach cramps. Should any of these side effects trouble you, speak with your physician. 

Q: Can METROGYL 400MG TABLET be used in patients with kidney problems?

– Use METROGYL 400MG TABLET with caution in patients with kidney problems, and consult your doctor before starting treatment.

Q: Can I consume alcohol while taking METROGYL 400MG TABLET?

– No, avoid alcohol consumption while taking METROGYL 400MG TABLET to prevent unpleasant side effects such as nausea, vomiting, stomach pain, irregular heartbeat, and headache. Consult your doctor immediately if you accidentally consume alcohol and experience these symptoms.

Q: How can I Buy or order METROGYL 400MG TABLET from Aum Pharmacy?

– You can Buy or order METROGYL 400MG TABLET online with a prescription at the best-discounted price from Aum Pharmacy. Search for the product, add it to your cart, and proceed to checkout. Aum Pharmacy is a leading online pharmacy in India.


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